定价： 515元 加购物车

4.1 Application of this guide will provide information on the acute toxicity of water-miscible metalworking fluids and will assist the user in evaluating the potential health hazards of the fluid and developing appropriate work practices. A water-miscible metalworking fluid is a concentrate designed to be diluted in water for use.4.2 Water-miscible metalworking fluids are complex chemical mixtures. The United States Occupational Safety and Health Administration (OSHA) Hazard Communication Standard (see A1.8) outlines procedures for the hazard determination of mixtures and states that if a mixture has not been tested as a whole, then the mixture shall be assumed to present the same hazards as do the components that comprise 1 % (by weight or volume) or greater of the mixture, except that the mixture shall be assumed to present a carcinogenic hazard if it contains a component in concentrations of 0.1 % or greater, which is considered to be a carcinogen (as defined in OSHA Standard 29 CFR 1910.1200). The determination of when to test a mixture as a whole and which toxicity tests are appropriate for the product must be made by a health professional qualified in evaluating toxicological data.4.3 Acute toxicology testing of water-miscible metalworking fluids consists of several individual tests including acute oral, dermal, or inhalation toxicity, eye irritation, skin irritation or corrosion, or both, skin sensitization, and sensory irritation. Certain protocols for acute oral, dermal, and inhalation toxicity tests are limit tests; further multi-dose testing (for example, Test Method E1103) should take place if mortality is noted on any of these tests. The referenced protocols specify the species and number of animals required. Selection of tests conducted should be designed to minimize the number of animals used.4.3.1 Acute Oral Toxicity—Acute oral toxicity tests (see A1.1) provide information on health hazards likely to arise from short-term exposure by the oral route. Results of this type of test are used to develop warning statements on labels as may be required by OSHA Hazard Communication Standard 29 CFR 1910.1200 (see A1.8) or Federal Hazardous Substances Act (see A1.10). These are also used to establish a dosage regimen for subchronic and other testing. Endpoint: mortality.4.3.2 Acute Dermal Toxicity—Acute dermal toxicity tests (see A1.2) provide information on health hazards likely to arise from short-term exposure by the dermal route and may provide initial information on dermal absorption and the mode of toxic action of a substance. In addition, some measure of irritation caused by the fluid may be obtained by observing local tissue damage at the sight of application. Endpoint: mortality.4.3.3 Acute Inhalation Toxicity—Acute inhalation toxicity tests give an indication of relative toxicity (see A1.3). The results provide an indication of the potential of the fluid to cause death and other adverse health effects when inhaled for a specified time period. Endpoint: mortality.4.3.4 Eye Irritation—Eye irritation tests provide an indication of the potential of the fluid to cause eye irritation or damage upon direct contact (see A1.4). An irritant is defined as a chemical that is not corrosive, but causes a reversible inflammatory effect on living tissue by chemical action at the site of contact. Endpoint: degree of irritation.4.3.5 Skin Irritation or Corrosion—Skin irritation or corrosion tests indicate the potential of the fluid to produce irritation or damage to skin (see A1.5). A corrosive chemical is one that causes visible destruction of, or irreversible alterations in, living tissue by chemical action at the site of contact. Endpoint: irritation or corrosion.4.3.6 Skin Sensitization—A chemical sensitizer is a material that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the chemical. A number of methods are available for measuring skin sensitization, however, there are differences in opinion on the most appropriate method. These are due to variations in compound administration and degree of reaction to a sensitizing substance. Refer to the Code of Federal Regulations (CFR) for the various protocols (see A1.6). Additionally, toxicology testing contract labs may have standard procedures for conducting these assays. Endpoint: sensitization.4.3.7 Sensory Irritation—Upon exposure to a sensory irritant, humans experience discomfort or a burning sensation of the eyes, nose, and throat, and may also cough. Test Method E981 (see A1.2.5) provides a means to evaluate the sensory irritant potential of airborne chemicals and mixtures, as well as a means to assess the comparative irritancy of compounds and formulations. However, this test method cannot be used to evaluate the relative obnoxiousness of odors. End point: upper respiratory tract irritation.4.4 A number of federal guidelines can be used to establish general procedures for testing acute toxicity of metalworking fluids. Several references are cited in Annex A1. Regardless of the method used, Good Laboratory Practices, as outlined by the United States Environmental Protection Agency (EPA 40 CFR 792) (see A1.9) must be followed. The OSHA Hazard Communication Standard (see A1.8) outlines the responsibilities of chemical manufacturers, importers, and employers in the determination of chemical hazards and communication of information on those hazards.4.5 The methods referenced in this guide, or appropriate alternate methods such as those suggested by the Organization for Economic Cooperation and Development (OECD), are acceptable for testing the acute toxicity of water-miscible metalworking fluids. For each test outlined in A1.1 – A1.5, a table is included that highlights the similarities and differences between the test protocols.1.1 This guide defines acute animal toxicity tests and sets forth the references for procedures to assess the acute toxicity of water-miscible metalworking fluids as manufactured.1.2 Although water-miscible metalworking fluids are typically used at high dilution, dilution rates vary widely. Additionally, there is potential for exposure to the metalworking fluid as manufactured.1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use.1.4 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.

定价： 590元 加购物车

5.1 Test Method D2968 for the determination of med and kemp fibers by microprojection may be used for the acceptance testing of commercial shipments of wool and other animal fibers, but caution is advised since only a few types of animal fibers have been subjected to interlaboratory tests to ascertain the precision of tests for med and kemp fibers by this test method. Comparative tests as directed in 5.1.1 may be advisable.5.1.1 In case of a dispute arising from differences in reported test results when using Test Method D2968 for acceptance testing of commercial shipments, the purchaser and the supplier should conduct comparative tests to determine if there is a statistical bias between their laboratories. Competent statistical assistance is recommended for the investigation of bias. As a minimum, the two parties should take a group of test specimens which are as homogeneous as possible and which are from a lot of material of the type in question. The test specimens should then be randomly assigned in equal numbers to each laboratory for testing. The average results from the two laboratories should be compared using Student's t-test for unpaired data and an acceptable probability level chosen by the two parties before testing is begun. If a bias is found, either its cause must be found and corrected, or the purchaser and the supplier must agree to interpret future test results in view of the known bias.5.2 Knowledge of the incidence of med fibers and kemp fibers in wool and other animal fibers is of importance to manufacturers of woven or knitted fabrics because of the apparent dye resistance and light reflectance qualities of these fibers. This is not to imply that all kemp fibers will resist dye and all med fibers will accept dye normally. In practice, a proportion of kemp fibers will appear normal after dyeing and a proportion of med fibers will appear chalky white after dyeing. From the perspective of visual and aesthetic problems, medullated fibers having an abnormally large diameter and a high degree of medullation are probably the worst kind.1.1 This test method covers the determination by microprojection of the percentage of medullated fibers (med and kemp fibers) in wool or other animal fibers such as mohair, cashmere, alpaca, or camel's hair in their various forms.1.2 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use.1.3 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.

定价： 515元 加购物车

定价： 590元 加购物车

定价： 590元 加购物车

5.1 This test method is considered satisfactory for acceptance testing of commercial shipments of wool and other animal fibers in raw and sliver form because current estimates of between-laboratory precision are acceptable. In cases of disagreement arising from differences in values reported by the purchaser and the supplier when using this test method for acceptance testing, Test Method D2130 shall be used as a referee method.5.2 This test method may be used for determining compliance with average fiber diameter and diameter variation to assign grades when determining conformance of shipments to material specifications given in Specifications D2252, D2816, D3991, and D3992.5.3 The procedures for determining mean fiber diameter and standard deviation of fiber diameter provided in this test method and in IWTO-12 are in essential agreement.1.1 This test method covers a procedure, using the Sirolan-Laserscan, for the determination of the average fiber diameter and the fiber diameter variation in wool and other animal fibers in their various forms.1.2 The values stated in SI units are to be regarded as the standard.1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use.1.4 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.

定价： 590元 加购物车

定价： 156元 / 折扣价： 133 元 加购物车

定价： 515元 加购物车

2.1 This test method is intended for the determination of the free fatty acids contained in animal, marine, and vegetable fats and oils for the purpose of quality assurance.1.1 This test method covers the determination of the free fatty acid content of fats and oils.1.2 The values stated in SI units are to be regarded as the standard. The values given in parentheses are for information only.1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use.1.4 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.

定价： 515元 加购物车

定价： 156元 / 折扣价： 133 元 加购物车

定价： 541元 / 折扣价： 482 元 加购物车

定价： 0元 加购物车

定价： 0元 加购物车

定价： 0元 加购物车

定价： 1532元